Development of the gonadotropin‐releasing hormone system
AH Duittoz, PE Forni, P Giacobini… - Journal of …, 2022 - Wiley Online Library
Journal of neuroendocrinology, 2022•Wiley Online Library
This review summarizes the current understanding of the development of the
neuroendocrine gonadotropin‐releasing hormone (GnRH) system, including discussion on
open questions regarding (1) transcriptional regulation of the Gnrh1 gene;(2) prenatal
development of the GnRH1 system in rodents and humans; and (3) paracrine and synaptic
communication during migration of the GnRH cells.
neuroendocrine gonadotropin‐releasing hormone (GnRH) system, including discussion on
open questions regarding (1) transcriptional regulation of the Gnrh1 gene;(2) prenatal
development of the GnRH1 system in rodents and humans; and (3) paracrine and synaptic
communication during migration of the GnRH cells.
Abstract
This review summarizes the current understanding of the development of the neuroendocrine gonadotropin‐releasing hormone (GnRH) system, including discussion on open questions regarding (1) transcriptional regulation of the Gnrh1 gene; (2) prenatal development of the GnRH1 system in rodents and humans; and (3) paracrine and synaptic communication during migration of the GnRH cells.
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